Continuous oral valproate vs placebo or no treatment: Recurrent seizure at 24 months
Continuous oral valproate showed no clear difference in recurrent seizure at 24 months compared with placebo or no treatment (low certainty).
What each review found
Include earlier review versions| Finding | Effect | Studies | GRADE certainty |
|---|---|---|---|
Continuous oral valproate vs placebo or no treatment Recurrent seizure at 24 months · children with febrile seizures Continuous oral valproate showed no clear difference in recurrent seizure at 24 months compared with placebo or no treatment (low certainty). Prophylactic drug management for febrile seizures in children (2021) · Cochrane Headline outcomes only | RR 1.26 [0.73, 2.18] | 2 studies · 156 participants | Low |
Findings are shown side by side, never pooled across reviews.
The reviews
| Review | Searched up to | Included studies | AMSTAR 2 |
|---|---|---|---|
| Prophylactic drug management for febrile seizures in children 2021 · Cochrane Headline outcomes only | Not reported | list not extracted yet | Not assessed |
Studies behind the findings
None of these reviews ties its included studies to this outcome in the data here. Cochrane reviews and reviews with headline outcomes only do not list their studies yet.
How reviews are matched to this question
Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.