Heat-killed probiotic and postbiotic oral lozenges vs placebo: Salivary Streptococcus mutans count and plaque index
- Population
- Adults with dental caries
- Intervention
- Heat-killed probiotic and postbiotic oral lozenges
- Comparison
- placebo
- Outcome
- Salivary Streptococcus mutans count and plaque index
No meta-analysis was conducted; postbiotic lozenges were reported to reduce salivary Streptococcus mutans counts and plaque index versus placebo.
What each review found
Include earlier review versions| Finding | Effect | Studies | GRADE certainty |
|---|---|---|---|
Heat-killed probiotic and postbiotic oral lozenges vs Placebo Salivary Streptococcus mutans count and plaque index · Adults with dental caries · 4 weeks, clinical setting No meta-analysis was conducted; postbiotic lozenges were reported to reduce salivary Streptococcus mutans counts and plaque index versus placebo. Postbiotics and Dental Caries: A Systematic Review. (2025) All outcomes | no estimate extracted | 1 study | GRADE not reported |
Findings are shown side by side, never pooled across reviews.
The reviews
| Review | Searched up to | Included studies | AMSTAR 2 |
|---|---|---|---|
| Postbiotics and Dental Caries: A Systematic Review. 2025 All outcomes | October 2024 | 21 | Critically Low / Critically Low |
Studies behind the findings
The primary studies the full-text reviews tie to this outcome. Reviews with headline outcomes only do not list them here.
- Impact of the food grade heat-killed probiotic and postbiotic oral lozenges in oral hygiene. · 2022 · included by 1 of these review
How reviews are matched to this question
Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.