Question · asked by 1 review

Lispro vs regular insulin (Different insulin types within similar insulin regimens): Pre‐eclampsia

Population
pregnant women with pre‐existing diabetes
Intervention
Lispro
Comparison
regular insulin (Different insulin types within similar insulin regimens)
Outcome
Pre‐eclampsia

It is very uncertain whether lispro changes pre‐eclampsia compared with regular insulin (Different insulin types within similar insulin… (very low certainty).

What each review found

Include earlier review versions
FindingEffectStudiesGRADE certainty
Lispro vs regular insulin (Different insulin types within similar insulin regimens)
Pre‐eclampsia · pregnant women with pre‐existing diabetes
It is very uncertain whether lispro changes pre‐eclampsia compared with regular insulin (Different insulin types within similar insulin… (very low certainty).
Different insulin types and regimens for pregnant women with pre‐existing diabetes (2017) · Cochrane Headline outcomes only
RR 0.68 [0.35, 1.3]1 study · 33 participantsVery low

Findings are shown side by side, never pooled across reviews.

The reviews

ReviewSearched up toIncluded studiesAMSTAR 2
Different insulin types and regimens for pregnant women with pre‐existing diabetes
2017 · Cochrane Headline outcomes only
Not reportedNot extractedNot assessed
How reviews are matched to this question

Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.