Question · asked by 1 review
Reduced dose of antipsychotics vs antipsychotic maintenance: Leaving the study early
- Population
- female and male 42 (mean) years old patients with schizophrenia or schizoaffective disorder and antipsychotic‐induced tardive dyskinesia
- Intervention
- Reduced dose of antipsychotics
- Comparison
- antipsychotic maintenance
- Outcome
- Leaving the study early
It is very uncertain whether reduced dose of antipsychotics changes acceptability of the treatment: leaving the study early compared with antipsychotic maintenance (very low certainty).
What each review found
Include earlier review versions| Finding | Effect | Studies | GRADE certainty |
|---|---|---|---|
Reduced dose of antipsychotics vs antipsychotic maintenance Acceptability of the treatment: leaving the study early · psychiatric patients (schizophrenia or schizoaffective disorder) with antipsychotic‐induced tardive dyskinesia It is very uncertain whether reduced dose of antipsychotics changes acceptability of the treatment: leaving the study early compared with antipsychotic maintenance (very low certainty). Antipsychotic reduction and/or cessation and antipsychotics as specific treatments for tardive dyskinesia (2018) · Cochrane Headline outcomes only | RR 0.33 [0.06, 1.99] | 1 study · 8 participants | Very low |
Findings are shown side by side, never pooled across reviews.
The reviews
| Review | Searched up to | Included studies | AMSTAR 2 |
|---|---|---|---|
| Antipsychotic reduction and/or cessation and antipsychotics as specific treatments for tardive dyskinesia 2018 · Cochrane Headline outcomes only | Not reported | Not extracted | Not assessed |
How reviews are matched to this question
Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.