Question · asked by 1 review
Lipopeptide antibiotic (daptomycin) vs aminoglycoside (low‐dose gentamicin) plus anti‐staphylococcal penicillin (nafcillin, oxacillin or flucloxacillin) or glycopeptide antibiotic (vancomycin): All‐cause mortality during hospital stay and all‐cause mortality at 1 year
- Population
- people with endocarditis caused by Staphylococcus aureus
- Intervention
- Lipopeptide antibiotic (daptomycin)
- Comparison
- aminoglycoside (low‐dose gentamicin) plus anti‐staphylococcal penicillin (nafcillin, oxacillin or flucloxacillin) or glycopeptide antibiotic (vancomycin)
- Outcome
- All‐cause mortality during hospital stay and all‐cause mortality at 1 year
The review found no eligible studies for this question.
What each review found
Include earlier review versions| Finding | Effect | Studies | GRADE certainty |
|---|---|---|---|
Lipopeptide antibiotic (daptomycin) vs aminoglycoside (low‐dose gentamicin) plus antistaphylococcal penicillin (nafcillin, oxacillin, or flucloxacillin) or glycopeptide antibiotic (vancomycin) All‐cause mortality during hospital stay and all‐cause mortality at 1 year1 · people with endocarditis caused by Staphylococcus aureus The review found no eligible studies for this question. A comparison of different antibiotic regimens for the treatment of infective endocarditis (2020) · Cochrane Headline outcomes only | no estimate extracted | Not reported | No studies found |
Findings are shown side by side, never pooled across reviews.
The reviews
| Review | Searched up to | Included studies | AMSTAR 2 |
|---|---|---|---|
| A comparison of different antibiotic regimens for the treatment of infective endocarditis 2020 · Cochrane Headline outcomes only | Not reported | Not extracted | Not assessed |
How reviews are matched to this question
Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.