Regular salmeterol vs placebo: All‐cause non‐fatal serious adverse events ‐ adults and adolescents
Regular salmeterol leads to higher all‐cause non‐fatal serious adverse events ‐ adults and adolescents compared with placebo (high certainty).
What each review found
Include earlier review versions| Finding | Effect | Studies | GRADE certainty |
|---|---|---|---|
Regular salmeterol vs placebo All‐cause non‐fatal serious adverse events ‐ adults and adolescents · patients with chronic asthma Regular salmeterol leads to higher all‐cause non‐fatal serious adverse events ‐ adults and adolescents compared with placebo (high certainty). Regular treatment with salmeterol for chronic asthma: serious adverse events (2008) · Cochrane Headline outcomes only | OR 1.14 [1.01, 1.28] | 13 studies · 30196 participants | High |
Findings are shown side by side, never pooled across reviews.
The reviews
| Review | Searched up to | Included studies | AMSTAR 2 |
|---|---|---|---|
| Regular treatment with salmeterol for chronic asthma: serious adverse events 2008 · Cochrane Headline outcomes only | Not reported | list not extracted yet | Not assessed |
Studies behind the findings
None of these reviews ties its included studies to this outcome in the data here. Cochrane reviews and reviews with headline outcomes only do not list their studies yet.
How reviews are matched to this question
Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.