Question · asked by 1 review
Absorbed drug (fluconazole or ketoconazole) vs Antifungal drugs not absorbed from GI tract: Mycological: eradication of oral candidiasis
- Population
- Patients with cancer receiving chemotherapy and/or radiotherapy with overt oral candidiasis
- Intervention
- Absorbed drug (fluconazole or ketoconazole)
- Comparison
- Antifungal drugs not absorbed from GI tract
- Outcome
- Mycological: eradication of oral candidiasis
Absorbed drug (fluconazole or ketoconazole) led to higher mycological: eradication of oral candidiasis compared with drug not absorbed from GI tract (amphotericin B or nystatin); GRADE not reported.
What each review found
Include earlier review versions| Finding | Effect | Studies | GRADE certainty |
|---|---|---|---|
Absorbed drug (fluconazole or ketoconazole) vs Drug not absorbed from GI tract (amphotericin B or nystatin) Mycological: eradication of oral candidiasis · Patients with cancer receiving chemotherapy and/or radiotherapy with overt oral candidiasis Absorbed drug (fluconazole or ketoconazole) led to higher mycological: eradication of oral candidiasis compared with drug not absorbed from GI tract (amphotericin B or nystatin); GRADE not reported. Interventions for treating oral candidiasis for patients with cancer receiving treatment (2010) · Cochrane All outcomes | RR 1.82 [1.28, 2.57] | 3 studies · 189 participants | GRADE not reported |
Findings are shown side by side, never pooled across reviews.
The reviews
| Review | Searched up to | Included studies | AMSTAR 2 |
|---|---|---|---|
| Interventions for treating oral candidiasis for patients with cancer receiving treatment 2010 · Cochrane All outcomes | 2010-06 | Not listed | Not assessed |
How reviews are matched to this question
Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.