38% silver diamine fluoride vs Fluoride varnish, glass ionomer cement, or placebo: Coronal carious lesions arrest
- Population
- Children with coronal carious lesions (primary dentition)
- Intervention
- 38% silver diamine fluoride
- Comparison
- Fluoride varnish, glass ionomer cement, or placebo
- Outcome
- Coronal carious lesions arrest
Across three reviews, 38% SDF arrested 65 to 91% of coronal lesions in primary teeth, outperforming fluoride varnish (38 to 44%), glass ionomer cement (39 to 82%), and placebo (34%) (ungraded).
What each review found
Include earlier review versions| Finding | Effect | Studies | GRADE certainty |
|---|---|---|---|
38% silver diamine fluoride vs Fluoride varnish, glass ionomer cement, or placebo Coronal carious lesions arrest (arrest rate) · Children with coronal carious lesions (primary dentition) · Primary dentition Across three reviews, 38% SDF arrested 65 to 91% of coronal lesions in primary teeth, outperforming fluoride varnish (38 to 44%), glass ionomer cement (39 to 82%), and placebo (34%) (ungraded). Silver diamine fluoride for managing carious lesions: an umbrella review. (2019) All outcomes | Arrest rate 65–91 | 6 studies | GRADE not reported |
Findings are shown side by side, never pooled across reviews.
The reviews
| Review | Searched up to | Included studies | AMSTAR 2 |
|---|---|---|---|
| Silver diamine fluoride for managing carious lesions: an umbrella review. 2019 All outcomes | June 2018 | 15 | Not applicable |
Related questions
The same intervention and outcome, asked in another population or against another comparator.
- 38% silver diamine fluoride vs placebo or no treatment · Children with coronal carious lesions (primary dentition) · 1 review
- 38% silver diamine fluoride vs Fluoride varnish or placebo · Children with coronal carious lesions (primary dentition) · 1 review
- 38% silver diamine fluoride vs placebo · Children with dental caries in permanent (first) molars · 1 review
- 38% silver diamine fluoride vs Fluoride varnish or atraumatic restorative treatment · Children with coronal carious lesions (primary dentition) · 1 review
How reviews are matched to this question
Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.