Question · asked by 1 review

Summary of Findings Table ‐ DaxibotulinumtoxinA 40U vs placebo: Total adverse events

Population
glabellar lines
Intervention
Summary of Findings Table ‐ DaxibotulinumtoxinA 40U
Comparison
placebo
Outcome
Total adverse events

Summary of Findings Table ‐ DaxibotulinumtoxinA 40U probably leads to higher total adverse events compared with placebo (moderate certainty).

What each review found

Include earlier review versions
FindingEffectStudiesGRADE certainty
Summary of Findings Table ‐ DaxibotulinumtoxinA 40U vs placebo
Total adverse events · glabellar lines
Summary of Findings Table ‐ DaxibotulinumtoxinA 40U probably leads to higher total adverse events compared with placebo (moderate certainty).
Botulinum toxin type A for facial wrinkles (2021) · Cochrane Headline outcomes only
RR 2.23 [1.46, 3.4]2 studies · 716 participantsModerate

Findings are shown side by side, never pooled across reviews.

The reviews

ReviewSearched up toIncluded studiesAMSTAR 2
Botulinum toxin type A for facial wrinkles
2021 · Cochrane Headline outcomes only
Not reportedNot extractedNot assessed
How reviews are matched to this question

Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.