Question · asked by 1 review

RAS inhibitors vs CCBs: All‐cause death

Population
patients with hypertension
Intervention
RAS inhibitors
Comparison
CCBs
Outcome
All‐cause death

RAS inhibitors showed no clear difference in all‐cause death compared with CCBs (moderate certainty).

What each review found

Include earlier review versions
FindingEffectStudiesGRADE certainty
RAS inhibitors vs CCBs
All‐cause death · people with hypertension
RAS inhibitors showed no clear difference in all‐cause death compared with CCBs (moderate certainty).
First‐line drugs inhibiting the renin angiotensin system versus other first‐line antihypertensive drug… (2018) · Cochrane Headline outcomes only
RR 1.03 [0.98, 1.09]5 studies · 35226 participantsModerate

Findings are shown side by side, never pooled across reviews.

The reviews

ReviewSearched up toIncluded studiesAMSTAR 2
First‐line drugs inhibiting the renin angiotensin system versus other first‐line antihypertensive drug classes for hypertension
2018 · Cochrane Headline outcomes only
Not reportedNot extractedNot assessed

The same intervention and outcome, asked in another population or against another comparator.

How reviews are matched to this question

Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.