Question · asked by 1 review
Living with HIV and undergoing antiretroviral therapy (ART/HAART) vs Healthy HIV-negative controls: Dental development / dental age (mineralization chronology)
- Population
- Children or adolescents
- Intervention
- Living with HIV and undergoing antiretroviral therapy (ART/HAART)
- Comparison
- Healthy HIV-negative controls
- Outcome
- Dental development / dental age (mineralization chronology)
No significant overall difference in dental development between CLWH on ART and healthy controls (three studies, narrative synthesis).
What each review found
Include earlier review versions| Finding | Effect | Studies | GRADE certainty |
|---|---|---|---|
Living with HIV and undergoing antiretroviral therapy (ART/HAART) vs Healthy HIV-negative controls Dental development / dental age (mineralization chronology) · Children and adolescents (<18 years) · Cross-sectional (case-control; single time point), HIV pediatric/ART clinics, AIDS centers, and hospitals in Brazil, India, Saudi Arabia, and West Africa (Cote d'Ivoire, Mali, Senegal) No significant overall difference in dental development between CLWH on ART and healthy controls (three studies, narrative synthesis). Oral Health Status of Children and Adolescents Living with HIV Undergoing Antiretroviral Therapy: A… (2022) All outcomes | Three studies (Fernandes 2007, de Souza 2015, Holderbaum 2005) assessed dental age (Nolla/Willems methods); Fernandes and de Souza found no significant difference between groups; Holderbaum reported mixed sex-specific… | 3 studies | GRADE not reported |
Findings are shown side by side, never pooled across reviews.
The reviews
| Review | Searched up to | Included studies | AMSTAR 2 |
|---|---|---|---|
| Oral Health Status of Children and Adolescents Living with HIV Undergoing Antiretroviral Therapy: A Systematic Review and Meta-Analysis. 2022 All outcomes | Inception to 29 July 2022 | 21 | Not applicable |
How reviews are matched to this question
Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.