Question · asked by 1 review

175 mg/m2 paclitaxel vs 250 mg/m2 paclitaxel: Overall survival

175 mg/m2 paclitaxel showed no clear difference in overall survival compared with 250 mg/m2 paclitaxel (low certainty).

What each review found

Include earlier review versions
FindingEffectStudiesGRADE certainty
175 mg/m2 paclitaxel vs 250 mg/m2 paclitaxel
Overall survival · women with recurrent epithelial ovarian cancer
175 mg/m2 paclitaxel showed no clear difference in overall survival compared with 250 mg/m2 paclitaxel (low certainty).
Taxane monotherapy regimens for the treatment of recurrent epithelial ovarian cancer (2022) · Cochrane Headline outcomes only
HR 0.97 [0.77, 1.23]1 study · 330 participantsLow

Findings are shown side by side, never pooled across reviews.

The reviews

ReviewSearched up toIncluded studiesAMSTAR 2
Taxane monotherapy regimens for the treatment of recurrent epithelial ovarian cancer
2022 · Cochrane Headline outcomes only
Not reportedlist not extracted yetNot assessed

Studies behind the findings

None of these reviews ties its included studies to this outcome in the data here. Cochrane reviews and reviews with headline outcomes only do not list their studies yet.

How reviews are matched to this question

Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.