Question · asked by 1 review

Insulin vs anti‐diabetic agent: Perinatal (fetal and neonatal death) and later infant mortality

Population
Infants of women diagnosed with gestational diabetes
Intervention
Insulin
Comparison
anti‐diabetic agent
Outcome
Perinatal (fetal and neonatal death) and later infant mortality

Insulin showed no clear difference in perinatal (fetal and neonatal death) and later infant mortality compared with anti‐diabetic agent (low certainty).

What each review found

Include earlier review versions
FindingEffectStudiesGRADE certainty
Insulin vs anti‐diabetic agent
Perinatal (fetal and neonatal death) and later infant mortality · Infants of women with gestational diabetes.
Insulin showed no clear difference in perinatal (fetal and neonatal death) and later infant mortality compared with anti‐diabetic agent (low certainty).
Insulin for the treatment of women with gestational diabetes (2017) · Cochrane Headline outcomes only
RR 0.85 [0.29, 2.49]10 studies · 1463 participantsLow

Findings are shown side by side, never pooled across reviews.

The reviews

ReviewSearched up toIncluded studiesAMSTAR 2
Insulin for the treatment of women with gestational diabetes
2017 · Cochrane Headline outcomes only
Not reportedNot extractedNot assessed
How reviews are matched to this question

Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.