Question · asked by 1 review
Clobetasol propionate plus miconazole (adjunctive antifungal) vs Clobetasol propionate plus placebo: Candidosis (adverse effect)
- Population
- People with symptomatic, biopsy-confirmed oral lichen planus (OLP); not concurrently receiving other OLP treatment
- Intervention
- Clobetasol propionate plus miconazole (adjunctive antifungal)
- Comparison
- Clobetasol propionate plus placebo
- Outcome
- Candidosis (adverse effect)
What each review found
Include earlier review versions| Finding | Effect | Studies | GRADE certainty |
|---|---|---|---|
Clobetasol propionate plus miconazole (adjunctive antifungal) vs Clobetasol propionate plus placebo Candidosis (adverse effect) · People with symptomatic, biopsy-confirmed oral lichen planus (OLP); not concurrently receiving other OLP treatment Interventions for treating oral lichen planus: corticosteroid therapies (2020) · Cochrane All outcomes | Lodi 2007: 5 cases of candidosis among 15 participants without antifungal vs 0 with adjunctive miconazole (low-certainty) | 1 study · 35 participants | Low |
Findings are shown side by side, never pooled across reviews.
The reviews
| Review | Searched up to | Included studies | AMSTAR 2 |
|---|---|---|---|
| Interventions for treating oral lichen planus: corticosteroid therapies 2020 · Cochrane All outcomes | 2019-02 | Not listed | Not assessed |
How reviews are matched to this question
Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.