Question · asked by 1 review

Any supplements containing iron and folic acid vs same supplements without iron nor folic acid (no iron nor folic acid or placebo): Maternal severe anaemia at any time during 2nd or 3rd trimester (Hb less than 70 g/L)

It is very uncertain whether (Maternal outcomes) Any supplements containing iron and folic acid changes maternal severe anaemia at any time during second and third… compared with same supplements without iron nor folic acid (no iron nor folic acid… (very low certainty).

What each review found

Include earlier review versions
FindingEffectStudiesGRADE certainty
(Maternal outcomes) Any supplements containing iron and folic acid vs same supplements without iron nor folic acid (no iron nor folic acid or placebo)
Maternal severe anaemia at any time during second and third trimester (Hb less than 70 g/L) (ALL) · Pregnant women of any gestational age and parity
It is very uncertain whether (Maternal outcomes) Any supplements containing iron and folic acid changes maternal severe anaemia at any time during second and third… compared with same supplements without iron nor folic acid (no iron nor folic acid… (very low certainty).
Daily oral iron supplementation during pregnancy (2015) · Cochrane Headline outcomes only
RR 0.12 [0.02, 0.63]4 studies · 506 participantsVery low

Findings are shown side by side, never pooled across reviews.

The reviews

ReviewSearched up toIncluded studiesAMSTAR 2
Daily oral iron supplementation during pregnancy
2015 · Cochrane Headline outcomes only
Not reportedlist not extracted yetNot assessed

Studies behind the findings

None of these reviews ties its included studies to this outcome in the data here. Cochrane reviews and reviews with headline outcomes only do not list their studies yet.

How reviews are matched to this question

Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.