Long‐acting beta2‐agonist plus tiotropium vs long‐acting beta2‐agonist alone: Hospital admissions
Long‐acting beta2‐agonist plus tiotropium showed no clear difference in hospital admission (all cause) compared with long‐acting beta2‐agonist alone (moderate certainty).
What each review found
Include earlier review versions| Finding | Effect | Studies | GRADE certainty |
|---|---|---|---|
Long‐acting beta2‐agonist plus tiotropium vs long‐acting beta2‐agonist alone Hospital admission (all cause) · addition to tiotropium versus either tiotropium or long‐acting beta2‐agonist alone for chronic obstructive pulmonary… Long‐acting beta2‐agonist plus tiotropium showed no clear difference in hospital admission (all cause) compared with long‐acting beta2‐agonist alone (moderate certainty). Long‐acting beta₂‐agonist in addition to tiotropium versus either tiotropium or long‐acting beta₂‐agonist… (2015) · Cochrane Headline outcomes only | OR 0.93 [0.76, 1.14] | 3 studies · 3514 participants | Moderate |
Findings are shown side by side, never pooled across reviews.
The reviews
| Review | Searched up to | Included studies | AMSTAR 2 |
|---|---|---|---|
| Long‐acting beta₂‐agonist in addition to tiotropium versus either tiotropium or long‐acting beta₂‐agonist alone for chronic obstructive… 2015 · Cochrane Headline outcomes only | Not reported | list not extracted yet | Not assessed |
Studies behind the findings
None of these reviews ties its included studies to this outcome in the data here. Cochrane reviews and reviews with headline outcomes only do not list their studies yet.
How reviews are matched to this question
Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.