Question · asked by 1 review

Lactulose vs lactitol: Hepatic encephalopathy

It is very uncertain whether lactulose changes hepatic encephalopathy compared with lactitol (very low certainty).

What each review found

Include earlier review versions
FindingEffectStudiesGRADE certainty
Lactulose vs lactitol
Hepatic encephalopathy · prevention and treatment of hepatic encephalopathy in people with cirrhosis
It is very uncertain whether lactulose changes hepatic encephalopathy compared with lactitol (very low certainty).
Non‐absorbable disaccharides versus placebo/no intervention and lactulose versus lactitol for the prevention… (2016) · Cochrane Headline outcomes only
RR 1 [0.84, 1.19]7 studies · 194 participantsVery low

Findings are shown side by side, never pooled across reviews.

The reviews

ReviewSearched up toIncluded studiesAMSTAR 2
Non‐absorbable disaccharides versus placebo/no intervention and lactulose versus lactitol for the prevention and treatment of hepatic…
2016 · Cochrane Headline outcomes only
Not reportedlist not extracted yetNot assessed

Studies behind the findings

None of these reviews ties its included studies to this outcome in the data here. Cochrane reviews and reviews with headline outcomes only do not list their studies yet.

How reviews are matched to this question

Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.