Question · asked by 1 review

Insulin vs anti‐diabetic agent: Large‐for‐gestational age

Population
Infants of women diagnosed with gestational diabetes
Intervention
Insulin
Comparison
anti‐diabetic agent
Outcome
Large‐for‐gestational age

Insulin showed no clear difference in large‐for‐gestational age (birthweight > 90th centile) compared with anti‐diabetic agent (moderate certainty).

What each review found

Include earlier review versions
FindingEffectStudiesGRADE certainty
Insulin vs anti‐diabetic agent
Large‐for‐gestational age (birthweight > 90th centile) · Infants of women with gestational diabetes.
Insulin showed no clear difference in large‐for‐gestational age (birthweight > 90th centile) compared with anti‐diabetic agent (moderate certainty).
Insulin for the treatment of women with gestational diabetes (2017) · Cochrane Headline outcomes only
RR 1.01 [0.76, 1.35]13 studies · 2352 participantsModerate

Findings are shown side by side, never pooled across reviews.

The reviews

ReviewSearched up toIncluded studiesAMSTAR 2
Insulin for the treatment of women with gestational diabetes
2017 · Cochrane Headline outcomes only
Not reportedNot extractedNot assessed
How reviews are matched to this question

Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.