Question · asked by 1 review

Electronic cigarette use vs Non-smokers (non-users): Dental caries and cariogenic bacteria (Streptococcus mutans, Lactobacilli)

Population
Adult e-cigarette (ENDS) users (general oral health; predominantly natural dentition)
Intervention
Electronic cigarette use
Comparison
Non-smokers (non-users)
Outcome
Dental caries and cariogenic bacteria (Streptococcus mutans, Lactobacilli)

E-cigarette use is associated with more cariogenic bacteria and increased dental caries risk compared with non-smokers (narrative synthesis; ungraded).

What each review found

Include earlier review versions
FindingEffectStudiesGRADE certainty
E-cigarette use (electronic nicotine delivery systems / vaping) vs Non-smokers (non-users)
Dental caries and cariogenic bacteria (Streptococcus mutans, Lactobacilli) · Adult e-cigarette (ENDS) users (general oral health; predominantly natural dentition) · Oral health / dental care (community and clinical samples)
E-cigarette use is associated with more cariogenic bacteria and increased dental caries risk compared with non-smokers (narrative synthesis; ungraded).
An Umbrella Review of E-Cigarettes' Impact on Oral Microbiota and Biofilm Buildup. (2025) All outcomes
Narrative synthesis: e-cigarette use linked to increased cariogenic bacteria (S. mutans, Lactobacilli) and worsening dental caries, with flavored e-liquids noted as a caries risk factor (Zieba, Camoni, Yang…3 studiesGRADE not reported

Findings are shown side by side, never pooled across reviews.

The reviews

ReviewSearched up toIncluded studiesAMSTAR 2
An Umbrella Review of E-Cigarettes' Impact on Oral Microbiota and Biofilm Buildup.
2025 All outcomes
12 March 202510Not applicable
How reviews are matched to this question

Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.