Question · asked by 1 review
Silver diamine fluoride (SDF) vs placebo: Treatment success (caries lesion arrest or restoration survival)
- Population
- Children (aged 3-11 y) with cavitated caries lesions in primary teeth
- Intervention
- Silver diamine fluoride (SDF)
- Comparison
- placebo
- Outcome
- Treatment success (caries lesion arrest or restoration survival)
At 6 months, SDF had significantly higher treatment success than placebo (OR 33.62).
What each review found
Include earlier review versions| Finding | Effect | Studies | GRADE certainty |
|---|---|---|---|
Silver diamine fluoride (SDF) vs Placebo Treatment success (caries lesion arrest or restoration survival) · Children (aged 3-11 y) with cavitated caries lesions in primary teeth · 6 months, Pediatric dentistry (primary teeth), 6-month follow-up At 6 months, SDF had significantly higher treatment success than placebo (OR 33.62). Comparative success of minimally invasive treatments for cavitated caries in primary teeth: a network… (2025) All outcomes | OR 33.62 [3.01, 375.92] | 44 studies | GRADE not reported |
Findings are shown side by side, never pooled across reviews.
The reviews
| Review | Searched up to | Included studies | AMSTAR 2 |
|---|---|---|---|
| Comparative success of minimally invasive treatments for cavitated caries in primary teeth: a network meta-analysis. 2025 All outcomes | November 2024 | 97 | Low / Critically Low |
How reviews are matched to this question
Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.