Question · asked by 1 review

Radioembolisation vs sorafenib monotherapy: Non‐serious adverse events (hand‐foot skin reaction)

Radioembolisation may leads to lower non‐serious adverse events (hand‐foot skin reaction) compared with sorafenib (low certainty).

What each review found

Include earlier review versions
FindingEffectStudiesGRADE certainty
Radioembolisation vs sorafenib
Non‐serious adverse events (hand‐foot skin reaction) · people with hepatocellular carcinoma
Radioembolisation may leads to lower non‐serious adverse events (hand‐foot skin reaction) compared with sorafenib (low certainty).
Yttrium-90 microsphere radioembolisation for unresectable hepatocellular carcinoma (2020) · Cochrane Headline outcomes only
RR 0.02 [0, 0.06]2 studies · 734 participantsLow

Findings are shown side by side, never pooled across reviews.

The reviews

ReviewSearched up toIncluded studiesAMSTAR 2
Yttrium-90 microsphere radioembolisation for unresectable hepatocellular carcinoma
2020 · Cochrane Headline outcomes only
Not reportedlist not extracted yetNot assessed

Studies behind the findings

None of these reviews ties its included studies to this outcome in the data here. Cochrane reviews and reviews with headline outcomes only do not list their studies yet.

How reviews are matched to this question

Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.