Resin infiltration vs Non-invasive measures (fluoride varnish/toothpaste, flossing, oral hygiene instruction, sham/standard of care): Radiographic proximal caries lesion progression
- Population
- Children and adults with non-cavitated proximal (interproximal) caries lesions in primary and/or permanent teeth (ages 3-45)
- Intervention
- Resin infiltration
- Comparison
- Non-invasive measures (fluoride varnish/toothpaste, flossing, oral hygiene instruction, sham/standard of care)
- Outcome
- Radiographic proximal caries lesion progression
Pooling 10 trials, resin infiltration reduced radiographic proximal caries progression versus non-invasive measures (OR 0.23); this subgroup was not separately GRADE-rated.
What each review found
Include earlier review versions| Finding | Effect | Studies | GRADE certainty |
|---|---|---|---|
Resin infiltration vs Non-invasive measures (fluoride varnish/toothpaste, flossing, oral hygiene instruction, sham/standard of care) Radiographic progression of proximal caries lesions · Children and adults with non-cavitated proximal (interproximal) caries lesions in primary and/or permanent teeth (ages… · Final follow-up (1 to 7 years across trials), Multiple countries (Brazil, Saudi Arabia, Netherlands, USA, Turkey, Switzerland, Germany, New Zealand, Chile, Thailand); dental clinic/community settings, Resin infiltration vs non-invasive (Fig. 5, subgroup 2.1.1) Pooling 10 trials, resin infiltration reduced radiographic proximal caries progression versus non-invasive measures (OR 0.23); this subgroup was not separately GRADE-rated. Microinvasive interventions in the management of proximal caries lesions in primary and permanent teeth-… (2025) All outcomes | OR 0.23 [0.15, 0.35] | 10 studies · 459 participants | GRADE not reported |
Findings are shown side by side, never pooled across reviews.
The reviews
| Review | Searched up to | Included studies | AMSTAR 2 |
|---|---|---|---|
| Microinvasive interventions in the management of proximal caries lesions in primary and permanent teeth- systematic review and… 2025 All outcomes | May 2024 | 17 | Low / Critically Low |
Related questions
The same intervention and outcome, asked in another population or against another comparator.
- Resin infiltration vs Non-invasive treatment · Patients with non-cavitated proximal (approximal) caries lesions (primary or permanent… · 1 review
How reviews are matched to this question
Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.