Question · asked by 1 review

Cetylpyridinium chloride + essential oils + chlorine dioxide + zinc mouthrinse (Breath Rx) vs placebo: Adverse events

Population
Adults over 18 years with a clinical or self-assessed diagnosis of halitosis, without significant comorbidity (e.g. diabetes) or refractory/severe chronic periodontal disease
Intervention
Cetylpyridinium chloride + essential oils + chlorine dioxide + zinc mouthrinse (Breath Rx)
Comparison
placebo
Outcome
Adverse events

What each review found

Include earlier review versions
FindingEffectStudiesGRADE certainty
Cetylpyridinium chloride + essential oils + chlorine dioxide + zinc mouthrinse (Breath Rx) vs Placebo
Adverse events · Adults over 18 years with a clinical or self-assessed diagnosis of halitosis, without significant comorbidity (e.g.… · 4 weeks
Mouthrinses for the treatment of halitosis (2008) · Cochrane All outcomes
Borden 2002: 13 adverse events were reported in the trial, but the investigators concluded that none were likely to be related to product usage.1 studyGRADE not reported

Findings are shown side by side, never pooled across reviews.

The reviews

ReviewSearched up toIncluded studiesAMSTAR 2
Mouthrinses for the treatment of halitosis
2008 · Cochrane All outcomes
2008-08Not listedNot assessed
How reviews are matched to this question

Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.