Question · asked by 1 review

Any pharmaceutical treatment vs placebo or no treatment: Side effects

It is very uncertain whether any pharmaceutical treatment changes side effects compared with placebo or no treatment (very low certainty).

What each review found

Include earlier review versions
FindingEffectStudiesGRADE certainty
Any pharmaceutical treatment vs placebo or no treatment
Side effects · pregnant women with heartburn in pregnancy
It is very uncertain whether any pharmaceutical treatment changes side effects compared with placebo or no treatment (very low certainty).
Interventions for heartburn in pregnancy (2015) · Cochrane Headline outcomes only
RR 0.63 [0.21, 1.89]2 studies · 256 participantsVery low

Findings are shown side by side, never pooled across reviews.

The reviews

ReviewSearched up toIncluded studiesAMSTAR 2
Interventions for heartburn in pregnancy
2015 · Cochrane Headline outcomes only
Not reportedlist not extracted yetNot assessed

Studies behind the findings

None of these reviews ties its included studies to this outcome in the data here. Cochrane reviews and reviews with headline outcomes only do not list their studies yet.

How reviews are matched to this question

Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.