Question · asked by 1 review
HALOPERIDOL vs ARIPIPRAZOLE: Adverse effects: any serious, specific ‐ dystonia during 24 hours
- Population
- patients with psychosis‐induced aggression or agitation
- Intervention
- HALOPERIDOL
- Comparison
- ARIPIPRAZOLE
- Outcome
- Adverse effects: any serious, specific ‐ dystonia during 24 hours
It is very uncertain whether HALOPERIDOL changes adverse effects: any serious, specific ‐ dystonia during 24 hours compared with OTHER ANTIPSYCHOTIC: a. ARIPIPRAZOLE (very low certainty).
What each review found
Include earlier review versions| Finding | Effect | Studies | GRADE certainty |
|---|---|---|---|
HALOPERIDOL vs OTHER ANTIPSYCHOTIC: a. ARIPIPRAZOLE Adverse effects: any serious, specific ‐ dystonia during 24 hours · patients with psychosis‐induced aggression or agitation It is very uncertain whether HALOPERIDOL changes adverse effects: any serious, specific ‐ dystonia during 24 hours compared with OTHER ANTIPSYCHOTIC: a. ARIPIPRAZOLE (very low certainty). Haloperidol for psychosis‐induced aggression or agitation (rapid tranquillisation) (2017) · Cochrane Headline outcomes only | RR 6.63 [1.52, 28.86] | 2 studies · 477 participants | Very low |
Findings are shown side by side, never pooled across reviews.
The reviews
| Review | Searched up to | Included studies | AMSTAR 2 |
|---|---|---|---|
| Haloperidol for psychosis‐induced aggression or agitation (rapid tranquillisation) 2017 · Cochrane Headline outcomes only | Not reported | Not extracted | Not assessed |
How reviews are matched to this question
Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.