Question · asked by 1 review

Alfentanil vs morphine: Daily mean opiate intake per hour

Population
People with cancer receiving chemotherapy or radiotherapy (or both) who have oral mucositis
Intervention
Alfentanil
Comparison
morphine
Outcome
Daily mean opiate intake per hour

Alfentanil led to lower daily mean opiate intake per hour compared with morphine; GRADE not reported.

What each review found

Include earlier review versions
FindingEffectStudiesGRADE certainty
Alfentanil vs Morphine
Daily mean opiate intake per hour · People with cancer receiving chemotherapy or radiotherapy (or both) who have oral mucositis
Alfentanil led to lower daily mean opiate intake per hour compared with morphine; GRADE not reported.
Interventions for treating oral mucositis for patients with cancer receiving treatment (2010) · Cochrane All outcomes
MD -3.90 [-6.42, -1.38]1 study · 28 participantsGRADE not reported

Findings are shown side by side, never pooled across reviews.

The reviews

ReviewSearched up toIncluded studiesAMSTAR 2
Interventions for treating oral mucositis for patients with cancer receiving treatment
2010 · Cochrane All outcomes
2010-06Not listedNot assessed
How reviews are matched to this question

Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.