Question · asked by 1 review

Gabapentin vs placebo: IMMPACT definition ‐ any at least moderate pain benefit

Population
adults with postherpetic neuralgia
Intervention
Gabapentin
Comparison
placebo
Outcome
IMMPACT definition ‐ any at least moderate pain benefit

What each review found

Include earlier review versions
FindingEffectStudiesGRADE certainty
Gabapentin vs placebo
IMMPACT definition ‐ any at least moderate pain benefit (includes Gong 2008 at 25% pain relief) · adults with postherpetic neuralgia
Gabapentin for chronic neuropathic pain in adults (2017) · Cochrane Headline outcomes only
no estimate extracted8 studies · 2260 participantsModerate

Findings are shown side by side, never pooled across reviews.

The reviews

ReviewSearched up toIncluded studiesAMSTAR 2
Gabapentin for chronic neuropathic pain in adults
2017 · Cochrane Headline outcomes only
Not reportedNot extractedNot assessed
How reviews are matched to this question

Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.