Question · asked by 1 review
Summary of findings: lorazepam plus haloperidol vs placebo plus haloperidol: Specific behaviour ‐ agitation
- Population
- terminally ill adults with severe delirium
- Intervention
- Summary of findings: lorazepam plus haloperidol
- Comparison
- placebo plus haloperidol
- Outcome
- Specific behaviour ‐ agitation
It is very uncertain whether summary of findings: lorazepam plus haloperidol changes agitation within 24 hoursc compared with placebo plus haloperidol (very low certainty).
What each review found
Include earlier review versionsNo studies found 1 · 50%GRADE not reported 0 · 0%Very low 1 · 50%Low 0 · 0%Moderate 0 · 0%High 0 · 0%
| Finding | Effect | Studies | GRADE certainty |
|---|---|---|---|
Summary of findings: lorazepam plus haloperidol vs placebo plus haloperidol Agitation within 24 hoursc · terminally ill adults with severe delirium It is very uncertain whether summary of findings: lorazepam plus haloperidol changes agitation within 24 hoursc compared with placebo plus haloperidol (very low certainty). Drug therapy for delirium in terminally ill adults (2020) · Cochrane Headline outcomes only | MD 1.9 | 1 study · 52 participants | Very low |
Summary of findings: lorazepam plus haloperidol vs placebo plus haloperidol Agitation between 24 and 48 hoursc · terminally ill adults with severe delirium The review found no eligible studies for this question. Drug therapy for delirium in terminally ill adults (2020) · Cochrane Headline outcomes only | no estimate extracted | Not reported | No studies found |
Findings are shown side by side, never pooled across reviews.
The reviews
| Review | Searched up to | Included studies | AMSTAR 2 |
|---|---|---|---|
| Drug therapy for delirium in terminally ill adults 2020 · Cochrane Headline outcomes only | Not reported | Not extracted | Not assessed |
How reviews are matched to this question
Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.