Question · asked by 1 review

1450 ppm F toothpaste vs 250 ppm F toothpaste: Caries increment, surface index D(M)FS

Population
Young children with primary (deciduous) dentition (aged 1 to 6 years at study start)
Intervention
1450 ppm F toothpaste
Comparison
250 ppm F toothpaste
Outcome
Caries increment, surface index D(M)FS

1450 ppm F toothpaste showed no clear difference in caries increment, surface index d(m)fs compared with 250 ppm F toothpaste (low certainty).

What each review found

Include earlier review versions
FindingEffectStudiesGRADE certainty
1450 ppm F toothpaste vs 250 ppm F toothpaste
Caries increment, surface index d(m)fs · Young children with primary (deciduous) dentition (aged 1 to 6 years at study start) · Follow-up: 22 months
1450 ppm F toothpaste showed no clear difference in caries increment, surface index d(m)fs compared with 250 ppm F toothpaste (low certainty).
Fluoride toothpastes of different concentrations for preventing dental caries (2019) · Cochrane All outcomes
MD -1.2 [-2.92, 0.52]1 study · 172 participantsLow

Findings are shown side by side, never pooled across reviews.

The reviews

ReviewSearched up toIncluded studiesAMSTAR 2
Fluoride toothpastes of different concentrations for preventing dental caries
2019 · Cochrane All outcomes
2018-08Not listedNot assessed
How reviews are matched to this question

Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.