Question · asked by 1 review

Budesonide 6 mg vs budesonide: Remission

Budesonide 6 mg showed no clear difference in continued remission at 3 months compared with budesonide 3 mg (moderate certainty).

What each review found

Include earlier review versions
FindingEffectStudiesGRADE certainty
Budesonide 6 mg vs budesonide 3 mg
Continued remission at 3 months · patients with quiescent Crohn's disease
Budesonide 6 mg showed no clear difference in continued remission at 3 months compared with budesonide 3 mg (moderate certainty).
Budesonide for maintenance of remission in Crohn's disease (2014) · Cochrane Headline outcomes only
RR 1.07 [0.85, 1.34]3 studies · 180 participantsModerate
Budesonide 6 mg vs budesonide 3 mg
Continued remission at 6 months · patients with quiescent Crohn's disease
Budesonide 6 mg showed no clear difference in continued remission at 6 months compared with budesonide 3 mg (moderate certainty).
Budesonide for maintenance of remission in Crohn's disease (2014) · Cochrane Headline outcomes only
RR 1.12 [0.85, 1.47]3 studies · 180 participantsModerate
Budesonide 6 mg vs budesonide 3 mg
Continued remission at 12 months · patients with quiescent Crohn's disease
Budesonide 6 mg showed no clear difference in continued remission at 12 months compared with budesonide 3 mg (moderate certainty).
Budesonide for maintenance of remission in Crohn's disease (2014) · Cochrane Headline outcomes only
RR 1.18 [0.85, 1.65]3 studies · 180 participantsModerate

Findings are shown side by side, never pooled across reviews.

The reviews

ReviewSearched up toIncluded studiesAMSTAR 2
Budesonide for maintenance of remission in Crohn's disease
2014 · Cochrane Headline outcomes only
Not reportedlist not extracted yetNot assessed

Studies behind the findings

None of these reviews ties its included studies to this outcome in the data here. Cochrane reviews and reviews with headline outcomes only do not list their studies yet.

How reviews are matched to this question

Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.