Imiquimod 5% cream with tazarotene 0.1% gel vs Imiquimod 5% cream alone: Secondary outcome: Inflammatory response (number of lesions with grade 2 or 3) Grade 2 or 3 Inflammation²
Imiquimod 5% cream with tazarotene 0.1% gel may leads to higher secondary outcome: Inflammatory response (number of lesions with… compared with imiquimod 5% cream alone (low certainty).
What each review found
Include earlier review versions| Finding | Effect | Studies | GRADE certainty |
|---|---|---|---|
Imiquimod 5% cream with tazarotene 0.1% gel vs Imiquimod 5% cream alone Secondary outcome: Inflammatory response (number of lesions with grade 2 or 3) Grade 2 or 3 Inflammation² · participants with melanoma in situ, including lentigo maligna Imiquimod 5% cream with tazarotene 0.1% gel may leads to higher secondary outcome: Inflammatory response (number of lesions with… compared with imiquimod 5% cream alone (low certainty). Interventions for melanoma in situ, including lentigo maligna (2014) · Cochrane Headline outcomes only | RR 1.38 [1.04, 1.84] | 1 study · 88 participants | Low |
Findings are shown side by side, never pooled across reviews.
The reviews
| Review | Searched up to | Included studies | AMSTAR 2 |
|---|---|---|---|
| Interventions for melanoma in situ, including lentigo maligna 2014 · Cochrane Headline outcomes only | Not reported | list not extracted yet | Not assessed |
Studies behind the findings
None of these reviews ties its included studies to this outcome in the data here. Cochrane reviews and reviews with headline outcomes only do not list their studies yet.
How reviews are matched to this question
Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.