Golimumab 50 mg every 4 weeks + MTX vs placebo + MTX: DAS (low or remission)
Golimumab 50 mg every 4 weeks + MTX leads to higher disease activity (DAS Remission) compared with placebo + MTX (high certainty).
What each review found
Include earlier review versions| Finding | Effect | Studies | GRADE certainty |
|---|---|---|---|
Golimumab 50 mg every 4 weeks + MTX vs placebo + MTX Disease activity (DAS Remission) · patients with rheumatoid arthritis Golimumab 50 mg every 4 weeks + MTX leads to higher disease activity (DAS Remission) compared with placebo + MTX (high certainty). Golimumab for rheumatoid arthritis (2010) · Cochrane Headline outcomes only | RR 5.12 [1.67, 15.66] | 4 studies · 919 participants | High |
Findings are shown side by side, never pooled across reviews.
The reviews
| Review | Searched up to | Included studies | AMSTAR 2 |
|---|---|---|---|
| Golimumab for rheumatoid arthritis 2010 · Cochrane Headline outcomes only | Not reported | list not extracted yet | Not assessed |
Studies behind the findings
None of these reviews ties its included studies to this outcome in the data here. Cochrane reviews and reviews with headline outcomes only do not list their studies yet.
How reviews are matched to this question
Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.