PDEI plus alpha‐blocker vs alpha‐blocker: Adverse effects
PDEI plus alpha‐blocker probably leads to higher adverse effects compared with alpha‐blockers alone (moderate certainty).
What each review found
Include earlier review versions| Finding | Effect | Studies | GRADE certainty |
|---|---|---|---|
PDEI plus alpha‐blocker vs alpha‐blockers alone Adverse effects PDEI plus alpha‐blocker probably leads to higher adverse effects compared with alpha‐blockers alone (moderate certainty). Phosphodiesterase inhibitors for lower urinary tract symptoms consistent with benign prostatic hyperplasia (2018) · Cochrane Headline outcomes only | RR 2.81 [1.53, 5.17] | 4 studies · 194 participants | Moderate |
Findings are shown side by side, never pooled across reviews.
The reviews
| Review | Searched up to | Included studies | AMSTAR 2 |
|---|---|---|---|
| Phosphodiesterase inhibitors for lower urinary tract symptoms consistent with benign prostatic hyperplasia 2018 · Cochrane Headline outcomes only | Not reported | list not extracted yet | Not assessed |
Studies behind the findings
None of these reviews ties its included studies to this outcome in the data here. Cochrane reviews and reviews with headline outcomes only do not list their studies yet.
How reviews are matched to this question
Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.