Question · asked by 1 review

Active NRT vs placebo ‐ rs16969968 ‐ non‐Hispanic black or African American: Abstinence

Active NRT showed no clear difference in abstinence at end of treatment compared with placebo ‐ rs16969968 ‐ non‐Hispanic black or African American (moderate certainty).

What each review found

Include earlier review versions
FindingEffectStudiesGRADE certainty
Active NRT vs placebo ‐ rs16969968 ‐ non‐Hispanic black or African American
Abstinence at end of treatment · people who smoke
Active NRT showed no clear difference in abstinence at end of treatment compared with placebo ‐ rs16969968 ‐ non‐Hispanic black or African American (moderate certainty).
Pharmacotherapy for smoking cessation: effects by subgroup defined by genetically informed biomarkers (2017) · Cochrane Headline outcomes only
RR 1.03 [0.36, 2.94]2 studies · 709 participantsModerate
Active NRT vs placebo ‐ rs16969968 ‐ non‐Hispanic black or African American
Abstinence at 6 months · people who smoke
Active NRT showed no clear difference in abstinence at 6 months compared with placebo ‐ rs16969968 ‐ non‐Hispanic black or African American (moderate certainty).
Pharmacotherapy for smoking cessation: effects by subgroup defined by genetically informed biomarkers (2017) · Cochrane Headline outcomes only
RR 1.11 [0.55, 2.26]2 studies · 709 participantsModerate

Findings are shown side by side, never pooled across reviews.

The reviews

ReviewSearched up toIncluded studiesAMSTAR 2
Pharmacotherapy for smoking cessation: effects by subgroup defined by genetically informed biomarkers
2017 · Cochrane Headline outcomes only
Not reportedlist not extracted yetNot assessed

Studies behind the findings

None of these reviews ties its included studies to this outcome in the data here. Cochrane reviews and reviews with headline outcomes only do not list their studies yet.

How reviews are matched to this question

Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.