Question · asked by 1 review

LAMA vs LABA: Pneumonia: high‐risk population

LAMA showed no clear difference in pneumonia: high‐risk population compared with LABA (moderate certainty).

What each review found

Include earlier review versions
FindingEffectStudiesGRADE certainty
LAMA vs LABA
Pneumonia: high‐risk population · chronic obstructive pulmonary disease with predicted FEV1 of less than 80%
LAMA showed no clear difference in pneumonia: high‐risk population compared with LABA (moderate certainty).
Dual combination therapy versus long‐acting bronchodilators alone for chronic obstructive pulmonary disease… (2018) · Cochrane Headline outcomes only
OR 0.83 [0.61, 1.13]2 studies · 10815 participantsModerate

Findings are shown side by side, never pooled across reviews.

The reviews

ReviewSearched up toIncluded studiesAMSTAR 2
Dual combination therapy versus long‐acting bronchodilators alone for chronic obstructive pulmonary disease (COPD): a systematic review…
2018 · Cochrane Headline outcomes only
Not reportedlist not extracted yetNot assessed

Studies behind the findings

None of these reviews ties its included studies to this outcome in the data here. Cochrane reviews and reviews with headline outcomes only do not list their studies yet.

How reviews are matched to this question

Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.