Question · asked by 1 review

Topical antibiotics with steroids vs topical antibiotics: Discomfort/pain

Population
people (of any age) with chronic suppurative otitis media or ear discharge
Intervention
Topical antibiotics with steroids
Comparison
topical antibiotics
Outcome
Discomfort/pain

It is very uncertain whether topical antibiotics with steroids changes ear pain or discomfort at 14 weeks compared with topical antibiotics alone (very low certainty).

What each review found

Include earlier review versions
FindingEffectStudiesGRADE certainty
Topical antibiotics with steroids vs topical antibiotics alone
Ear pain or discomfort at 14 weeks · people (of any age) with chronic suppurative otitis media or ear discharge
It is very uncertain whether topical antibiotics with steroids changes ear pain or discomfort at 14 weeks compared with topical antibiotics alone (very low certainty).
Topical antibiotics with steroids for chronic suppurative otitis media (2020) · Cochrane Headline outcomes only
RR 1.08 [0.07, 16.36]1 study · 52 participantsVery low

Findings are shown side by side, never pooled across reviews.

The reviews

ReviewSearched up toIncluded studiesAMSTAR 2
Topical antibiotics with steroids for chronic suppurative otitis media
2020 · Cochrane Headline outcomes only
Not reportedNot extractedNot assessed
How reviews are matched to this question

Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.