Cetylpyridinium chloride (CPC) vs Water: Reduction in level of contamination by particles >5 um (droplets) at <2 m from patient's oral cavity
- Population
- Dental patients undergoing aerosol-generating procedures (AGPs) and the dental healthcare providers treating them
- Intervention
- Cetylpyridinium chloride (CPC)
- Comparison
- Water
- Outcome
- Reduction in level of contamination by particles >5 um (droplets) at <2 m from patient's oral cavity
Cetylpyridinium chloride (CPC) may leads to lower reduction in level of contamination by particles >5 um (droplets) at… compared with water (low certainty).
What each review found
Include earlier review versions| Finding | Effect | Studies | GRADE certainty |
|---|---|---|---|
Cetylpyridinium chloride (CPC) vs Water Reduction in level of contamination by particles >5 um (droplets) at <2 m from patient's oral cavity · Dental patients undergoing aerosol-generating procedures (AGPs) and the dental healthcare providers treating them · CPC+Zn+F vs water; operator level Cetylpyridinium chloride (CPC) may leads to lower reduction in level of contamination by particles >5 um (droplets) at… compared with water (low certainty). Preprocedural mouth rinses for preventing transmission of infectious diseases through aerosols in dental… (2022) · Cochrane All outcomes | MD -246 [-437.96, -54.04] | 1 study · 30 participants | Low |
Cetylpyridinium chloride (CPC) vs Water Reduction in level of contamination by particles >5 um (droplets) at <2 m from patient's oral cavity · Dental patients undergoing aerosol-generating procedures (AGPs) and the dental healthcare providers treating them · CPC + domiphen bromide + quaternary ammonium vs water; combined It is very uncertain whether cetylpyridinium chloride (CPC) changes reduction in level of contamination by particles >5 um (droplets) at… compared with water (very low certainty). Preprocedural mouth rinses for preventing transmission of infectious diseases through aerosols in dental… (2022) · Cochrane All outcomes | MD -0.78 [-1.24, -0.31] | 1 study · 105 participants | Very low |
Cetylpyridinium chloride (CPC) vs Water Reduction in level of contamination by particles >5 um (droplets) at <2 m from patient's oral cavity · Dental patients undergoing aerosol-generating procedures (AGPs) and the dental healthcare providers treating them · CPC vs water; operator level It is very uncertain whether cetylpyridinium chloride (CPC) changes reduction in level of contamination by particles >5 um (droplets) at… compared with water (very low certainty). Preprocedural mouth rinses for preventing transmission of infectious diseases through aerosols in dental… (2022) · Cochrane All outcomes | MD -48.7 [-67.82, -29.58] | 1 study · 30 participants | Very low |
Findings are shown side by side, never pooled across reviews.
The reviews
| Review | Searched up to | Included studies | AMSTAR 2 |
|---|---|---|---|
| Preprocedural mouth rinses for preventing transmission of infectious diseases through aerosols in dental healthcare providers 2022 · Cochrane All outcomes | 2022-02 | Not listed | Not assessed |
Related questions
The same intervention and outcome, asked in another population or against another comparator.
- Cetylpyridinium chloride (CPC) vs No rinsing · Dental patients undergoing aerosol-generating procedures (AGPs) and the dental… · 1 review
How reviews are matched to this question
Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.