Question · asked by 1 review
Prophylactic prostaglandin E (oral) vs placebo: Viral isolates
- Population
- Patients being treated for cancer (leukaemia)
- Intervention
- Prophylactic prostaglandin E (oral)
- Comparison
- placebo
- Outcome
- Viral isolates
Prophylactic prostaglandin E (oral) led to higher viral isolates compared with placebo; GRADE not reported.
What each review found
Include earlier review versions| Finding | Effect | Studies | GRADE certainty |
|---|---|---|---|
Prophylactic prostaglandin E (oral) vs Placebo Viral isolates · Patients being treated for cancer (leukaemia) Prophylactic prostaglandin E (oral) led to higher viral isolates compared with placebo; GRADE not reported. Interventions for the prevention and treatment of herpes simplex virus in patients being treated for cancer (2009) · Cochrane All outcomes | RR 1.87 [1.12, 3.14] | 1 study · 60 participants | GRADE not reported |
Findings are shown side by side, never pooled across reviews.
The reviews
| Review | Searched up to | Included studies | AMSTAR 2 |
|---|---|---|---|
| Interventions for the prevention and treatment of herpes simplex virus in patients being treated for cancer 2009 · Cochrane All outcomes | 2008-11 | Not listed | Not assessed |
How reviews are matched to this question
Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.