Adalimumab vs placebo: Improved IBDQ at week 8
Adalimumab probably leads to higher improved IBDQ at week 8 compared with placebo (moderate certainty).
What each review found
Include earlier review versions| Finding | Effect | Studies | GRADE certainty |
|---|---|---|---|
Adalimumab vs placebo Improved IBDQ at week 8 · patients with active ulcerative colitis Adalimumab probably leads to higher improved IBDQ at week 8 compared with placebo (moderate certainty). The impact of biological interventions for ulcerative colitis on health‐related quality of life (2015) · Cochrane Headline outcomes only | RR 1.23 [1.06, 1.43] | 2 studies · 767 participants | Moderate |
Findings are shown side by side, never pooled across reviews.
The reviews
| Review | Searched up to | Included studies | AMSTAR 2 |
|---|---|---|---|
| The impact of biological interventions for ulcerative colitis on health‐related quality of life 2015 · Cochrane Headline outcomes only | Not reported | list not extracted yet | Not assessed |
Studies behind the findings
None of these reviews ties its included studies to this outcome in the data here. Cochrane reviews and reviews with headline outcomes only do not list their studies yet.
How reviews are matched to this question
Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.