Benzoyl peroxide vs adapalene: Adverse event data
- Population
- participants with acne
- Intervention
- Benzoyl peroxide
- Comparison
- adapalene
- Outcome
- Adverse event data
It is very uncertain whether benzoyl peroxide changes total number of participants with any adverse events (long‐term… compared with adapalene (very low certainty).
What each review found
Include earlier review versions| Finding | Effect | Studies | GRADE certainty |
|---|---|---|---|
Benzoyl peroxide vs adapalene Total number of participants with any adverse events (long‐term data) Treatment duration: range 11 weeks to 24 weeks · acne vulgaris It is very uncertain whether benzoyl peroxide changes total number of participants with any adverse events (long‐term… compared with adapalene (very low certainty). Topical benzoyl peroxide for acne (2020) · Cochrane Headline outcomes only | RR 0.71 [0.5, 1] | 7 studies · 2120 participants | Very low |
Findings are shown side by side, never pooled across reviews.
The reviews
| Review | Searched up to | Included studies | AMSTAR 2 |
|---|---|---|---|
| Topical benzoyl peroxide for acne 2020 · Cochrane Headline outcomes only | Not reported | Not extracted | Not assessed |
Related questions
The same intervention and outcome, asked in another population or against another comparator.
- Benzoyl peroxide vs erythromycin · participants with acne · 1 review
How reviews are matched to this question
Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.