Question · asked by 1 review
Fluoride varnish vs Non-fluoride (placebo) varnish: Adverse effects
- Population
- Orthodontic patients of any age with fixed braces (new DLs assessed at debond)
- Intervention
- Fluoride varnish
- Comparison
- Non-fluoride (placebo) varnish
- Outcome
- Adverse effects
What each review found
Include earlier review versions| Finding | Effect | Studies | GRADE certainty |
|---|---|---|---|
Professionally-applied fluoride varnish (7700 or 10,000 ppm F), every 6 weeks vs Non-fluoride (placebo) varnish Adverse effects · Orthodontic patients of any age with fixed braces (new DLs assessed at debond) · At debond; follow-up 1.7 years Fluorides for preventing early tooth decay (demineralised lesions) during fixed brace treatment (2019) · Cochrane All outcomes | SoF 1. Adverse effects: no evidence that the intervention had adverse effects; only 1 participant with an adverse event and unclear if directly related to the intervention. 148 participants (1 RCT, Sonesson 2019);… | 1 study · 148 participants | Low |
Findings are shown side by side, never pooled across reviews.
The reviews
| Review | Searched up to | Included studies | AMSTAR 2 |
|---|---|---|---|
| Fluorides for preventing early tooth decay (demineralised lesions) during fixed brace treatment 2019 · Cochrane All outcomes | 1 February 2019 | Not listed | Not assessed |
How reviews are matched to this question
Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.