TNF‐alpha antagonists vs placebo: IBDQ at weeks 6 or 8
TNF‐alpha antagonists leads to higher improved IBDQ at weeks 6 or 8 compared with placebo (high certainty).
What each review found
Include earlier review versions| Finding | Effect | Studies | GRADE certainty |
|---|---|---|---|
TNF‐alpha antagonists vs placebo Improved IBDQ at weeks 6 or 8 · patients with active ulcerative colitis TNF‐alpha antagonists leads to higher improved IBDQ at weeks 6 or 8 compared with placebo (high certainty). The impact of biological interventions for ulcerative colitis on health‐related quality of life (2015) · Cochrane Headline outcomes only | RR 1.32 [1.19, 1.46] | 3 studies · 1495 participants | High |
TNF‐alpha antagonists vs placebo IBDQ at weeks 6 or 8 · patients with active ulcerative colitis The impact of biological interventions for ulcerative colitis on health‐related quality of life (2015) · Cochrane Headline outcomes only | no estimate extracted | 4 studies · 1565 participants | Moderate |
Findings are shown side by side, never pooled across reviews.
The reviews
| Review | Searched up to | Included studies | AMSTAR 2 |
|---|---|---|---|
| The impact of biological interventions for ulcerative colitis on health‐related quality of life 2015 · Cochrane Headline outcomes only | Not reported | list not extracted yet | Not assessed |
Studies behind the findings
None of these reviews ties its included studies to this outcome in the data here. Cochrane reviews and reviews with headline outcomes only do not list their studies yet.
How reviews are matched to this question
Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.