Question · asked by 1 review

An extended NVP regimen administered to infants for 6 weeks vs sdNVP: Genotypic Resistance to NVP among Indian infants HIV‐infected through late breastfeeding Standard Population Sequencing

Population
Breastfeeding infants of HIV‐infected mothers
Intervention
An extended NVP regimen administered to infants for 6 weeks
Comparison
sdNVP
Outcome
Genotypic Resistance to NVP among Indian infants HIV‐infected through late breastfeeding Standard Population Sequencing

An extended NVP regimen administered to infants for 6 weeks showed no clear difference in genotypic Resistance to NVP among Indian infants HIV‐infected… compared with sdNVP (low certainty).

What each review found

Include earlier review versions
FindingEffectStudiesGRADE certainty
An extended NVP regimen administered to infants for 6 weeks vs sdNVP
Genotypic Resistance to NVP among Indian infants HIV‐infected through late breastfeeding Standard Population Sequencing · Breastfeeding infants of HIV‐infected mothers
An extended NVP regimen administered to infants for 6 weeks showed no clear difference in genotypic Resistance to NVP among Indian infants HIV‐infected… compared with sdNVP (low certainty).
Antiretroviral interventions for preventing breast milk transmission of HIV (2014) · Cochrane Headline outcomes only
RR 1.03 [0.2, 5.33]1 study · 33 participantsLow

Findings are shown side by side, never pooled across reviews.

The reviews

ReviewSearched up toIncluded studiesAMSTAR 2
Antiretroviral interventions for preventing breast milk transmission of HIV
2014 · Cochrane Headline outcomes only
Not reportedNot extractedNot assessed
How reviews are matched to this question

Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.