Question · asked by 0 reviews

Antifibrinolytic therapy (tranexamic acid or epsilon aminocaproic acid) vs Placebo, no intervention or usual care (with or without placebo): Side effects or other adverse events

Population
People of all ages on VKA or DOAC treatment undergoing oral or dental procedures (therapeutic INR 2.0 to 4.0; people using acetylsalicylic acid excluded)
Intervention
Antifibrinolytic therapy (tranexamic acid or epsilon aminocaproic acid)
Comparison
Placebo, no intervention or usual care (with or without placebo)
Outcome
Side effects or other adverse events

What each review found

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The reviews

ReviewSearched up toIncluded studiesAMSTAR 2

The same intervention and outcome, asked in another population or against another comparator.

How reviews are matched to this question

Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.