Question · asked by 1 review

Carboxymethylcellulose (CMC) mouthwash vs Glycerin mouthwash: Improvement in dry mouth ('excellent benefit', dichotomous)

Population
Adults seeking treatment for the symptom of dry mouth (xerostomia) due to any cause (e.g. medication, Sjogren's syndrome, radiotherapy, haemodialysis)
Intervention
Carboxymethylcellulose (CMC) mouthwash
Comparison
Glycerin mouthwash
Outcome
Improvement in dry mouth ('excellent benefit', dichotomous)

Carboxymethylcellulose (CMC) mouthwash led to higher improvement in dry mouth ('excellent benefit', dichotomous) compared with glycerin mouthwash; GRADE not reported.

What each review found

Include earlier review versions
FindingEffectStudiesGRADE certainty
Carboxymethylcellulose (CMC) mouthwash vs Glycerin mouthwash
Improvement in dry mouth ('excellent benefit', dichotomous) · Adults seeking treatment for the symptom of dry mouth (xerostomia) due to any cause (e.g. medication, Sjogren's…
Carboxymethylcellulose (CMC) mouthwash led to higher improvement in dry mouth ('excellent benefit', dichotomous) compared with glycerin mouthwash; GRADE not reported.
Interventions for the management of dry mouth: topical therapies (2011) · Cochrane All outcomes
RR 3.95 [1.17, 13.36]1 study · 148 participantsGRADE not reported

Findings are shown side by side, never pooled across reviews.

The reviews

ReviewSearched up toIncluded studiesAMSTAR 2
Interventions for the management of dry mouth: topical therapies
2011 · Cochrane All outcomes
2011-10Not listedNot assessed
How reviews are matched to this question

Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.