Question · asked by 1 review
Topical NSAID (ketoprofen lysinate mouthwash, 160 mg) vs Topical NSAID (benzidamine hydrochloride mouthwash, 22.5 mg): Patient‐reported pain intensity or pain relief (VAS, NRS or categorical scale)
- Population
- People undergoing orthodontic treatment (any age; 9 to 34 years in included studies)
- Intervention
- Topical NSAID (ketoprofen lysinate mouthwash, 160 mg)
- Comparison
- Topical NSAID (benzidamine hydrochloride mouthwash, 22.5 mg)
- Outcome
- Patient‐reported pain intensity or pain relief (VAS, NRS or categorical scale)
What each review found
Include earlier review versions| Finding | Effect | Studies | GRADE certainty |
|---|---|---|---|
Topical NSAID (ketoprofen lysinate mouthwash, 160 mg) vs Topical NSAID (benzidamine hydrochloride mouthwash, 22.5 mg) Pain intensity (VAS) · People undergoing orthodontic treatment (any age; 9 to 34 years in included studies) · 4 days (not usable) Pharmacological interventions for pain relief during orthodontic treatment (2017) · Cochrane All outcomes | One study (Lauritano 2000) compared ketoprofen 160 mg with benzidamine chloride 22.5 mg mouthwashes; it presented data at 4 days only, so the data could not be used in this review; no GRADE rating. | 1 study | GRADE not reported |
Findings are shown side by side, never pooled across reviews.
The reviews
| Review | Searched up to | Included studies | AMSTAR 2 |
|---|---|---|---|
| Pharmacological interventions for pain relief during orthodontic treatment 2017 · Cochrane All outcomes | 2017-06-19 | Not listed | Not assessed |
How reviews are matched to this question
Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.