Question · asked by 1 review

Itraconazole vs Fluconazole: Death associated with fungal infection

Population
Patients with cancer receiving chemotherapy and/or radiotherapy
Intervention
Itraconazole
Comparison
Fluconazole
Outcome
Death associated with fungal infection

Itraconazole showed no clear difference in death associated with fungal infection compared with fluconazole; GRADE not reported.

What each review found

Include earlier review versions
FindingEffectStudiesGRADE certainty
Itraconazole vs Fluconazole
Death associated with fungal infection · Patients with cancer receiving chemotherapy or radiotherapy or both
Itraconazole showed no clear difference in death associated with fungal infection compared with fluconazole; GRADE not reported.
Interventions for preventing oral candidiasis for patients with cancer receiving treatment (2007) · Cochrane All outcomes
RR 0.14 [0.01, 2.73]1 study · 202 participantsGRADE not reported

Findings are shown side by side, never pooled across reviews.

The reviews

ReviewSearched up toIncluded studiesAMSTAR 2
Interventions for preventing oral candidiasis for patients with cancer receiving treatment
2007 · Cochrane All outcomes
2009-08Not listedNot assessed
How reviews are matched to this question

Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.