Question · asked by 1 review
HIGH DOSE (greater than or equal to 10 mg/day) vs ANY DOSE ‐ short term: Leaving the study early: insufficient response ‐ When compared with ultra low dose (<2 mg/day)
- Population
- patients with schizophrenia
- Intervention
- HIGH DOSE (greater than or equal to 10 mg/day)
- Comparison
- ANY DOSE ‐ short term
- Outcome
- Leaving the study early: insufficient response ‐ When compared with ultra low dose (<2 mg/day)
HIGH DOSE (greater than or equal to 10 mg/day) probably leads to lower leaving the study early: insufficient response ‐ When compared with… compared with ANY DOSE ‐ short term (moderate certainty).
What each review found
Include earlier review versions| Finding | Effect | Studies | GRADE certainty |
|---|---|---|---|
HIGH DOSE (greater than or equal to 10 mg/day) vs ANY DOSE ‐ short term Leaving the study early: insufficient response ‐ When compared with ultra low dose (<2 mg/day) · patients with schizophrenia HIGH DOSE (greater than or equal to 10 mg/day) probably leads to lower leaving the study early: insufficient response ‐ When compared with… compared with ANY DOSE ‐ short term (moderate certainty). Risperidone dose for schizophrenia (2009) · Cochrane Headline outcomes only | RR 0.66 [0.45, 0.97] | 1 study · 679 participants | Moderate |
Findings are shown side by side, never pooled across reviews.
The reviews
| Review | Searched up to | Included studies | AMSTAR 2 |
|---|---|---|---|
| Risperidone dose for schizophrenia 2009 · Cochrane Headline outcomes only | Not reported | Not extracted | Not assessed |
How reviews are matched to this question
Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.