Angiotensin‐converting enzyme inhibitors vs placebo or no treatment: Fatal or nonfatal stroke
- Population
- people with diabetes and kidney disease
- Intervention
- Angiotensin‐converting enzyme inhibitors
- Comparison
- placebo or no treatment
- Outcome
- Fatal or nonfatal stroke
Angiotensin‐converting‐enzyme inhibitors showed no clear difference in fatal or nonfatal stroke Median compared with placebo or no treatment (low certainty).
What each review found
Include earlier review versions| Finding | Effect | Studies | GRADE certainty |
|---|---|---|---|
Angiotensin‐converting‐enzyme inhibitors vs placebo or no treatment Fatal or nonfatal stroke Median · people with diabetes and kidney disease Angiotensin‐converting‐enzyme inhibitors showed no clear difference in fatal or nonfatal stroke Median compared with placebo or no treatment (low certainty). Angiotensin‐converting‐enzyme inhibitors and angiotensin receptor blockers for preventing the progression of… (2024) · Cochrane Headline outcomes only | RR 1.02 [0.8, 1.31] | 2 studies · 4944 participants | Low |
Findings are shown side by side, never pooled across reviews.
The reviews
| Review | Searched up to | Included studies | AMSTAR 2 |
|---|---|---|---|
| Angiotensin‐converting‐enzyme inhibitors and angiotensin receptor blockers for preventing the progression of diabetic kidney disease 2024 · Cochrane Headline outcomes only | Not reported | Not extracted | Not assessed |
Related questions
The same intervention and outcome, asked in another population or against another comparator.
- Angiotensin‐converting enzyme inhibitors vs ACEi plus angiotensin receptor blockers · people with diabetes and kidney disease · 1 review
- Angiotensin‐converting enzyme inhibitors vs another ACEi · people with diabetes and kidney disease · 1 review
How reviews are matched to this question
Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.