Question · asked by 1 review

Ursodeoxycholic acid vs placebo or no treatment: All‐cause mortality at 100 days post‐transplant

Summary of findings: Ursodeoxycholic acid may leads to lower all‐cause mortality at 100 days post‐transplant ( compared with placebo or no treatment (low certainty).

What each review found

Include earlier review versions
FindingEffectStudiesGRADE certainty
Summary of findings: Ursodeoxycholic acid vs placebo or no treatment
All‐cause mortality at 100 days post‐transplant ( · People undergoing stem cell transplant with a variety of malignant and non‐malignant diseases
Summary of findings: Ursodeoxycholic acid may leads to lower all‐cause mortality at 100 days post‐transplant ( compared with placebo or no treatment (low certainty).
Interventions for prophylaxis of hepatic veno‐occlusive disease in people undergoing haematopoietic stem… (2015) · Cochrane Headline outcomes only
RR 0.7 [0.5, 0.99]4 studies · 612 participantsLow

Findings are shown side by side, never pooled across reviews.

The reviews

ReviewSearched up toIncluded studiesAMSTAR 2
Interventions for prophylaxis of hepatic veno‐occlusive disease in people undergoing haematopoietic stem cell transplantation
2015 · Cochrane Headline outcomes only
Not reportedlist not extracted yetNot assessed

Studies behind the findings

None of these reviews ties its included studies to this outcome in the data here. Cochrane reviews and reviews with headline outcomes only do not list their studies yet.

How reviews are matched to this question

Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.